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Characterization of GLPG0492, a selective androgen receptor modulator, in a mouse model of hindlimb immobilization

BACKGROUND: Muscle wasting is a hallmark of many chronic conditions but also of aging and results in a progressive functional decline leading ultimately to disability. Androgens, such as testosterone were proposed as therapy to counteract muscle atrophy. However, this treatment is associated with po...

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Detalles Bibliográficos
Autores principales: Blanqué, Roland, Lepescheux, Liên, Auberval, Marielle, Minet, Dominique, Merciris, Didier, Cottereaux, Céline, Clément-Lacroix, Philippe, Delerive, Philippe, Namour, Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167280/
https://www.ncbi.nlm.nih.gov/pubmed/25185887
http://dx.doi.org/10.1186/1471-2474-15-291

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