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Bachelors, Divorcees, and Widowers: Does Marriage Protect Men from Type 2 Diabetes?

While research has suggested that being married may confer a health advantage, few studies to date have investigated the role of marital status in the development of type 2 diabetes. We examined whether men who are not married have increased risk of incident type 2 diabetes in the Health Professiona...

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Autores principales: Cornelis, Marilyn C., Chiuve, Stephanie E., Glymour, M. Maria, Chang, Shun-Chiao, Tchetgen Tchetgen, Eric J., Liang, Liming, Koenen, Karestan C., Rimm, Eric B., Kawachi, Ichiro, Kubzansky, Laura D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167705/
https://www.ncbi.nlm.nih.gov/pubmed/25229473
http://dx.doi.org/10.1371/journal.pone.0106720
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author Cornelis, Marilyn C.
Chiuve, Stephanie E.
Glymour, M. Maria
Chang, Shun-Chiao
Tchetgen Tchetgen, Eric J.
Liang, Liming
Koenen, Karestan C.
Rimm, Eric B.
Kawachi, Ichiro
Kubzansky, Laura D.
author_facet Cornelis, Marilyn C.
Chiuve, Stephanie E.
Glymour, M. Maria
Chang, Shun-Chiao
Tchetgen Tchetgen, Eric J.
Liang, Liming
Koenen, Karestan C.
Rimm, Eric B.
Kawachi, Ichiro
Kubzansky, Laura D.
author_sort Cornelis, Marilyn C.
collection PubMed
description While research has suggested that being married may confer a health advantage, few studies to date have investigated the role of marital status in the development of type 2 diabetes. We examined whether men who are not married have increased risk of incident type 2 diabetes in the Health Professionals Follow-up Study. Men (n = 41,378) who were free of T2D in 1986, were followed for ≤22 years with biennial reports of T2D, marital status and covariates. Cox proportional hazard models were used to compare risk of incident T2D by marital status (married vs unmarried and married vs never married, divorced/separated, or widowed). There were 2,952 cases of incident T2D. Compared to married men, unmarried men had a 16% higher risk of developing T2D (95%CI:1.04,1.30), adjusting for age, family history of diabetes, ethnicity, lifestyle and body mass index (BMI). Relative risks (RR) for developing T2D differed for divorced/separated (1.09 [95%CI: 0.94,1.27]), widowed (1.29 [95%CI:1.06,1.57]), and never married (1.17 [95%CI:0.91,1.52]) after adjusting for age, family history of diabetes and ethnicity. Adjusting for lifestyle and BMI, the RR for T2D associated with widowhood was no longer significant (RR:1.16 [95%CI:0.95,1.41]). When allowing for a 2-year lag period between marital status and disease, RRs of T2D for widowers were augmented and borderline significant (RR:1.24 [95%CI:1.00,1.54]) after full adjustment. In conclusion, not being married, and more specifically, widowhood was more consistently associated with an increased risk of type 2 diabetes in men and this may be mediated, in part, through unfavorable changes in lifestyle, diet and adiposity.
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spelling pubmed-41677052014-09-22 Bachelors, Divorcees, and Widowers: Does Marriage Protect Men from Type 2 Diabetes? Cornelis, Marilyn C. Chiuve, Stephanie E. Glymour, M. Maria Chang, Shun-Chiao Tchetgen Tchetgen, Eric J. Liang, Liming Koenen, Karestan C. Rimm, Eric B. Kawachi, Ichiro Kubzansky, Laura D. PLoS One Research Article While research has suggested that being married may confer a health advantage, few studies to date have investigated the role of marital status in the development of type 2 diabetes. We examined whether men who are not married have increased risk of incident type 2 diabetes in the Health Professionals Follow-up Study. Men (n = 41,378) who were free of T2D in 1986, were followed for ≤22 years with biennial reports of T2D, marital status and covariates. Cox proportional hazard models were used to compare risk of incident T2D by marital status (married vs unmarried and married vs never married, divorced/separated, or widowed). There were 2,952 cases of incident T2D. Compared to married men, unmarried men had a 16% higher risk of developing T2D (95%CI:1.04,1.30), adjusting for age, family history of diabetes, ethnicity, lifestyle and body mass index (BMI). Relative risks (RR) for developing T2D differed for divorced/separated (1.09 [95%CI: 0.94,1.27]), widowed (1.29 [95%CI:1.06,1.57]), and never married (1.17 [95%CI:0.91,1.52]) after adjusting for age, family history of diabetes and ethnicity. Adjusting for lifestyle and BMI, the RR for T2D associated with widowhood was no longer significant (RR:1.16 [95%CI:0.95,1.41]). When allowing for a 2-year lag period between marital status and disease, RRs of T2D for widowers were augmented and borderline significant (RR:1.24 [95%CI:1.00,1.54]) after full adjustment. In conclusion, not being married, and more specifically, widowhood was more consistently associated with an increased risk of type 2 diabetes in men and this may be mediated, in part, through unfavorable changes in lifestyle, diet and adiposity. Public Library of Science 2014-09-17 /pmc/articles/PMC4167705/ /pubmed/25229473 http://dx.doi.org/10.1371/journal.pone.0106720 Text en © 2014 Cornelis et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Cornelis, Marilyn C.
Chiuve, Stephanie E.
Glymour, M. Maria
Chang, Shun-Chiao
Tchetgen Tchetgen, Eric J.
Liang, Liming
Koenen, Karestan C.
Rimm, Eric B.
Kawachi, Ichiro
Kubzansky, Laura D.
Bachelors, Divorcees, and Widowers: Does Marriage Protect Men from Type 2 Diabetes?
title Bachelors, Divorcees, and Widowers: Does Marriage Protect Men from Type 2 Diabetes?
title_full Bachelors, Divorcees, and Widowers: Does Marriage Protect Men from Type 2 Diabetes?
title_fullStr Bachelors, Divorcees, and Widowers: Does Marriage Protect Men from Type 2 Diabetes?
title_full_unstemmed Bachelors, Divorcees, and Widowers: Does Marriage Protect Men from Type 2 Diabetes?
title_short Bachelors, Divorcees, and Widowers: Does Marriage Protect Men from Type 2 Diabetes?
title_sort bachelors, divorcees, and widowers: does marriage protect men from type 2 diabetes?
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167705/
https://www.ncbi.nlm.nih.gov/pubmed/25229473
http://dx.doi.org/10.1371/journal.pone.0106720
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