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The Transcriptional Specificity of NF-κB Dimers Is Coded within the κB DNA Response Elements
Nuclear factor κB (NF-κB) regulates gene expression by binding to specific DNA elements, known collectively as κB sites, that are contained within the promoters/enhancers of target genes. We found that the identity of the central base pair (bp) of κB sites profoundly affects the transcriptional acti...
Autores principales: | Wang, Vivien Ya-Fan, Huang, Wendy, Asagiri, Masataka, Spann, Nathanael, Hoffmann, Alexander, Glass, Christopher, Ghosh, Gourisankar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167904/ https://www.ncbi.nlm.nih.gov/pubmed/23063365 http://dx.doi.org/10.1016/j.celrep.2012.08.042 |
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