Discovery of a new ATP-binding motif involved in peptidic azoline biosynthesis

Despite intensive research, the cyclodehydratase responsible for azoline biogenesis in thiazole/oxazole-modified microcin (TOMM) natural products remains enigmatic. The collaboration of two proteins, C and D, is required for cyclodehydration. The C protein is homologous to E1 ubiquitin-activating en...

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Detalles Bibliográficos
Autores principales: Dunbar, Kyle L., Chekan, Jonathan R., Cox, Courtney L., Burkhart, Brandon J., Nair, Satish K., Mitchell, Douglas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167974/
https://www.ncbi.nlm.nih.gov/pubmed/25129028
http://dx.doi.org/10.1038/nchembio.1608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167974/
https://www.ncbi.nlm.nih.gov/pubmed/25129028
http://dx.doi.org/10.1038/nchembio.1608

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