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Discovery of a new ATP-binding motif involved in peptidic azoline biosynthesis
Despite intensive research, the cyclodehydratase responsible for azoline biogenesis in thiazole/oxazole-modified microcin (TOMM) natural products remains enigmatic. The collaboration of two proteins, C and D, is required for cyclodehydration. The C protein is homologous to E1 ubiquitin-activating en...
Autores principales: | Dunbar, Kyle L., Chekan, Jonathan R., Cox, Courtney L., Burkhart, Brandon J., Nair, Satish K., Mitchell, Douglas A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167974/ https://www.ncbi.nlm.nih.gov/pubmed/25129028 http://dx.doi.org/10.1038/nchembio.1608 |
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