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Minocycline Enhances the Effectiveness of Nociceptin/Orphanin FQ during Neuropathic Pain

Nociceptin/orphanin FQ (N/OFQ) antinociception, which is mediated selectively by the N/OFQ peptide receptor (NOP), was demonstrated in pain models. In this study, we determine the role of activated microglia on the analgesic effects of N/OFQ in a rat model of neuropathic pain induced by chronic cons...

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Detalles Bibliográficos
Autores principales: Popiolek-Barczyk, Katarzyna, Rojewska, Ewelina, Jurga, Agnieszka M., Makuch, Wioletta, Zador, Ferenz, Borsodi, Anna, Piotrowska, Anna, Przewlocka, Barbara, Mika, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168034/
https://www.ncbi.nlm.nih.gov/pubmed/25276817
http://dx.doi.org/10.1155/2014/762930

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