Activation of Pro-survival CaMK4β/CREB and Pro-death MST1 signaling at early and late times during a mouse model of prion disease

BACKGROUND: The signaling pathways most critical to prion disease pathogenesis are as yet incompletely characterized. We have developed a kinomics approach to identify signaling pathways that are dysregulated during prion pathogenesis. The approach is sensitive and specific enough to detect signalin...

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Detalles Bibliográficos
Autores principales: Shott, Rory H, Majer, Anna, Frost, Kathy L, Booth, Stephanie A, Schang, Luis M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168054/
https://www.ncbi.nlm.nih.gov/pubmed/25183307
http://dx.doi.org/10.1186/1743-422X-11-160

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