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Risk Factors for Death during Pulmonary Tuberculosis Treatment in Korea: A Multicenter Retrospective Cohort Study
The data regarding risk factors for death during tuberculosis (TB) treatment are inconsistent, and few studies examined this issue in Korea. The purpose of this study was to evaluate baseline prognostic factors for death during treatment of adult patients with pulmonary TB in Korea. A multicenter re...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Academy of Medical Sciences
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168175/ https://www.ncbi.nlm.nih.gov/pubmed/25246740 http://dx.doi.org/10.3346/jkms.2014.29.9.1226 |
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author | Kwon, Yong-Soo Kim, Yee Hyung Song, Jae-Uk Jeon, Kyeongman Song, Junwhi Ryu, Yon Ju Choi, Jae Chol Kim, Ho Cheol Koh, Won-Jung |
author_facet | Kwon, Yong-Soo Kim, Yee Hyung Song, Jae-Uk Jeon, Kyeongman Song, Junwhi Ryu, Yon Ju Choi, Jae Chol Kim, Ho Cheol Koh, Won-Jung |
author_sort | Kwon, Yong-Soo |
collection | PubMed |
description | The data regarding risk factors for death during tuberculosis (TB) treatment are inconsistent, and few studies examined this issue in Korea. The purpose of this study was to evaluate baseline prognostic factors for death during treatment of adult patients with pulmonary TB in Korea. A multicenter retrospective cohort study of 2,481 patients who received TB treatment at eight hospitals from January 2009 to December 2010 was performed. Successful treatment included cure (1,129, 45.5%) and treatment completion (1,204, 48.5%) in 2,333 patients (94.0%). Unsuccessful treatment included death (85, 3.4%) and treatment failure (63, 2.5%) occurred in 148 patients (6.0%). In multivariate analysis, male sex, anemia, dyspnea, chronic heart disease, malignancy, and intensive care unit (ICU) admission were significant risk factors for death during TB treatment. Therefore, male sex, anemia, dyspnea, chronic heart disease, malignancy, and ICU admission could be baseline prognostic factors for death during treatment of adult patients with pulmonary TB in Korea. GRAPHICAL ABSTRACT: [Image: see text] |
format | Online Article Text |
id | pubmed-4168175 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | The Korean Academy of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-41681752014-09-22 Risk Factors for Death during Pulmonary Tuberculosis Treatment in Korea: A Multicenter Retrospective Cohort Study Kwon, Yong-Soo Kim, Yee Hyung Song, Jae-Uk Jeon, Kyeongman Song, Junwhi Ryu, Yon Ju Choi, Jae Chol Kim, Ho Cheol Koh, Won-Jung J Korean Med Sci Original Article The data regarding risk factors for death during tuberculosis (TB) treatment are inconsistent, and few studies examined this issue in Korea. The purpose of this study was to evaluate baseline prognostic factors for death during treatment of adult patients with pulmonary TB in Korea. A multicenter retrospective cohort study of 2,481 patients who received TB treatment at eight hospitals from January 2009 to December 2010 was performed. Successful treatment included cure (1,129, 45.5%) and treatment completion (1,204, 48.5%) in 2,333 patients (94.0%). Unsuccessful treatment included death (85, 3.4%) and treatment failure (63, 2.5%) occurred in 148 patients (6.0%). In multivariate analysis, male sex, anemia, dyspnea, chronic heart disease, malignancy, and intensive care unit (ICU) admission were significant risk factors for death during TB treatment. Therefore, male sex, anemia, dyspnea, chronic heart disease, malignancy, and ICU admission could be baseline prognostic factors for death during treatment of adult patients with pulmonary TB in Korea. GRAPHICAL ABSTRACT: [Image: see text] The Korean Academy of Medical Sciences 2014-09 2014-09-02 /pmc/articles/PMC4168175/ /pubmed/25246740 http://dx.doi.org/10.3346/jkms.2014.29.9.1226 Text en © 2014 The Korean Academy of Medical Sciences. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Kwon, Yong-Soo Kim, Yee Hyung Song, Jae-Uk Jeon, Kyeongman Song, Junwhi Ryu, Yon Ju Choi, Jae Chol Kim, Ho Cheol Koh, Won-Jung Risk Factors for Death during Pulmonary Tuberculosis Treatment in Korea: A Multicenter Retrospective Cohort Study |
title | Risk Factors for Death during Pulmonary Tuberculosis Treatment in Korea: A Multicenter Retrospective Cohort Study |
title_full | Risk Factors for Death during Pulmonary Tuberculosis Treatment in Korea: A Multicenter Retrospective Cohort Study |
title_fullStr | Risk Factors for Death during Pulmonary Tuberculosis Treatment in Korea: A Multicenter Retrospective Cohort Study |
title_full_unstemmed | Risk Factors for Death during Pulmonary Tuberculosis Treatment in Korea: A Multicenter Retrospective Cohort Study |
title_short | Risk Factors for Death during Pulmonary Tuberculosis Treatment in Korea: A Multicenter Retrospective Cohort Study |
title_sort | risk factors for death during pulmonary tuberculosis treatment in korea: a multicenter retrospective cohort study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168175/ https://www.ncbi.nlm.nih.gov/pubmed/25246740 http://dx.doi.org/10.3346/jkms.2014.29.9.1226 |
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