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Pharmacokinetic and Pharmacodynamic Profiles of Canagliflozin in Japanese Patients with Type 2 Diabetes Mellitus and Moderate Renal Impairment
BACKGROUND AND OBJECTIVES: This study examined the effects of moderate renal impairment on the pharmacokinetics and pharmacodynamics of canagliflozin in Japanese patients with type 2 diabetes mellitus. METHODS: Japanese patients with stable type 2 diabetes (12 with moderate renal impairment and 12 w...
Autores principales: | Inagaki, Nobuya, Kondo, Kazuoki, Yoshinari, Toru, Ishii, Manabu, Sakai, Masaki, Kuki, Hideki, Furihata, Kenichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168221/ https://www.ncbi.nlm.nih.gov/pubmed/25200141 http://dx.doi.org/10.1007/s40261-014-0226-x |
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