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Cross-Talk between cAMP and MAPK Pathways in HSD11B2 Induction by hCG in Placental Trophoblasts
Overexposure of the fetus to glucocorticoids in gestation is detrimental to fetal development. The passage of maternal glucocorticoids into the fetal circulation is governed by 11beta-Hydroxysteroid Dehydrogenase Type 2 (HSD11B2) in the placental syncytiotrophoblasts. Human chorionic gonadotropin (h...
Autores principales: | Shu, Qun, Li, Wenjiao, Li, Jianneng, Wang, Wangsheng, Liu, Chao, Sun, Kang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168233/ https://www.ncbi.nlm.nih.gov/pubmed/25229504 http://dx.doi.org/10.1371/journal.pone.0107938 |
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