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5-Lipoxygenase Inhibitors Attenuate TNF-α-Induced Inflammation in Human Synovial Fibroblasts

The lipoxygenase isoform of 5-lipoxygenase (5-LOX) is reported to be overexpressed in human rheumatoid arthritis synovial tissue and involved in the progress of inflammatory arthritis. However, the detailed mechanism of how 5-lipoxygenase regulates the inflammatory response in arthritis synovial tis...

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Detalles Bibliográficos
Autores principales:	Lin, Han-Ching, Lin, Tzu-Hung, Wu, Ming-Yueh, Chiu, Yung-Cheng, Tang, Chih-Hsin, Hour, Mann-Jen, Liou, Houng-Chi, Tu, Huang-Ju, Yang, Rong-Sen, Fu, Wen-Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168259/ https://www.ncbi.nlm.nih.gov/pubmed/25229347 http://dx.doi.org/10.1371/journal.pone.0107890

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