Cargando…
Key regulators control distinct transcriptional programmes in blood progenitor and mast cells
Despite major advances in the generation of genome-wide binding maps, the mechanisms by which transcription factors (TFs) regulate cell type identity have remained largely obscure. Through comparative analysis of 10 key haematopoietic TFs in both mast cells and blood progenitors, we demonstrate that...
Autores principales: | Calero-Nieto, Fernando J, Ng, Felicia S, Wilson, Nicola K, Hannah, Rebecca, Moignard, Victoria, Leal-Cervantes, Ana I, Jimenez-Madrid, Isabel, Diamanti, Evangelia, Wernisch, Lorenz, Göttgens, Berthold |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168288/ https://www.ncbi.nlm.nih.gov/pubmed/24760698 http://dx.doi.org/10.1002/embj.201386825 |
Ejemplares similares
-
Shared transcription factors contribute to distinct cell fates
por: Ng, Felicia SL, et al.
Publicado: (2015) -
A graphical model approach visualizes regulatory relationships between genome-wide transcription factor binding profiles
por: Ng, Felicia S L, et al.
Publicado: (2016) -
Constrained transcription factor spacing is prevalent and important for transcriptional control of mouse blood cells
por: Ng, Felicia SL, et al.
Publicado: (2014) -
Transcriptional mechanisms of cell fate decisions revealed by single cell expression profiling
por: Moignard, Victoria, et al.
Publicado: (2014) -
Gene set control analysis predicts hematopoietic control mechanisms from genome-wide transcription factor binding data
por: Joshi, Anagha, et al.
Publicado: (2013)