Population pharmacokinetics of levodopa in subjects with advanced Parkinson's disease: levodopa-carbidopa intestinal gel infusion vs. oral tablets

AIMS: Levodopa-carbidopa intestinal gel (LCIG) provides continuous levodopa-carbidopa delivery through intrajejunal infusion. This study characterized the population pharmacokinetics of levodopa following a 16 h jejunal infusion of LCIG or frequent oral administration of levodopa-carbidopa tablets (...

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Detalles Bibliográficos
Autores principales: Othman, Ahmed A, Dutta, Sandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2014
Materias:
Pharmacokinetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168384/
https://www.ncbi.nlm.nih.gov/pubmed/24433449
http://dx.doi.org/10.1111/bcp.12324

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