The Cerebrovascular Basement Membrane: Role in the Clearance of β-amyloid and Cerebral Amyloid Angiopathy

Cerebral amyloid angiopathy (CAA), the accumulation of β-amyloid (Aβ) peptides in the walls of cerebral blood vessels, is observed in the majority of Alzheimer’s disease (AD) brains and is thought to be due to a failure of the aging brain to clear Aβ. Perivascular drainage of Aβ along cerebrovascula...

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Detalles Bibliográficos
Autores principales: Morris, Alan W. J., Carare, Roxana O., Schreiber, Stefanie, Hawkes, Cheryl A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168721/
https://www.ncbi.nlm.nih.gov/pubmed/25285078
http://dx.doi.org/10.3389/fnagi.2014.00251

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