Novel somatic single nucleotide variants within the RNA binding protein hnRNP A1 in multiple sclerosis patients

Some somatic single nucleotide variants (SNVs) are thought to be pathogenic, leading to neurological disease. We hypothesized that heterogeneous nuclear ribonuclear protein A1 (hnRNP A1), an autoantigen associated with multiple sclerosis (MS) would contain SNVs. MS patients develop antibodies to hnR...

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Detalles Bibliográficos
Autores principales: Lee, Sangmin, Levin, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168748/
https://www.ncbi.nlm.nih.gov/pubmed/25254102
http://dx.doi.org/10.12688/f1000research.4436.2

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