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Atmin mediates kidney morphogenesis by modulating Wnt signaling
The DNA damage protein and transcription factor Atmin (Asciz) is required for both lung tubulogenesis and ciliogenesis. Like the lungs, kidneys contain a tubular network that is critical for their function and in addition, renal ciliary dysfunction has been implicated in the pathogenesis of cystic k...
Autores principales: | Goggolidou, Paraskevi, Hadjirin, Nazreen F., Bak, Aggie, Papakrivopoulou, Eugenia, Hilton, Helen, Norris, Dominic P., Dean, Charlotte H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168818/ https://www.ncbi.nlm.nih.gov/pubmed/24852369 http://dx.doi.org/10.1093/hmg/ddu246 |
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