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PEGylated versus non-PEGylated magnetic nanoparticles as camptothecin delivery system

Camptothecin (CPT; (S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione) is a highly cytotoxic natural alkaloid that has not yet found use as chemotherapeutic agent due to its poor water-solubility and chemical instability and, as a consequence, no e...

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Detalles Bibliográficos
Autores principales: Castillo, Paula M, de la Mata, Mario, Casula, Maria F, Sánchez-Alcázar, José A, Zaderenko, Ana P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168894/
https://www.ncbi.nlm.nih.gov/pubmed/25247114
http://dx.doi.org/10.3762/bjnano.5.144