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Application of cyclic phosphonamide reagents in the total synthesis of natural products and biologically active molecules
A review of the synthesis of natural products and bioactive compounds adopting phosphonamide anion technology is presented highlighting the utility of phosphonamide reagents in stereocontrolled bond-forming reactions. Methodologies utilizing phosphonamide anions in asymmetric alkylations, Michael ad...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Beilstein-Institut
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168934/ https://www.ncbi.nlm.nih.gov/pubmed/25246946 http://dx.doi.org/10.3762/bjoc.10.195 |
| _version_ | 1782335644768403456 |
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| author | Focken, Thilo Hanessian, Stephen |
| author_facet | Focken, Thilo Hanessian, Stephen |
| author_sort | Focken, Thilo |
| collection | PubMed |
| description | A review of the synthesis of natural products and bioactive compounds adopting phosphonamide anion technology is presented highlighting the utility of phosphonamide reagents in stereocontrolled bond-forming reactions. Methodologies utilizing phosphonamide anions in asymmetric alkylations, Michael additions, olefinations, and cyclopropanations will be summarized, as well as an overview of the synthesis of the employed phosphonamide reagents. |
| format | Online Article Text |
| id | pubmed-4168934 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2014 |
| publisher | Beilstein-Institut |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-41689342014-09-22 Application of cyclic phosphonamide reagents in the total synthesis of natural products and biologically active molecules Focken, Thilo Hanessian, Stephen Beilstein J Org Chem Review A review of the synthesis of natural products and bioactive compounds adopting phosphonamide anion technology is presented highlighting the utility of phosphonamide reagents in stereocontrolled bond-forming reactions. Methodologies utilizing phosphonamide anions in asymmetric alkylations, Michael additions, olefinations, and cyclopropanations will be summarized, as well as an overview of the synthesis of the employed phosphonamide reagents. Beilstein-Institut 2014-08-13 /pmc/articles/PMC4168934/ /pubmed/25246946 http://dx.doi.org/10.3762/bjoc.10.195 Text en Copyright © 2014, Focken and Hanessian https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms) |
| spellingShingle | Review Focken, Thilo Hanessian, Stephen Application of cyclic phosphonamide reagents in the total synthesis of natural products and biologically active molecules |
| title | Application of cyclic phosphonamide reagents in the total synthesis of natural products and biologically active molecules |
| title_full | Application of cyclic phosphonamide reagents in the total synthesis of natural products and biologically active molecules |
| title_fullStr | Application of cyclic phosphonamide reagents in the total synthesis of natural products and biologically active molecules |
| title_full_unstemmed | Application of cyclic phosphonamide reagents in the total synthesis of natural products and biologically active molecules |
| title_short | Application of cyclic phosphonamide reagents in the total synthesis of natural products and biologically active molecules |
| title_sort | application of cyclic phosphonamide reagents in the total synthesis of natural products and biologically active molecules |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168934/ https://www.ncbi.nlm.nih.gov/pubmed/25246946 http://dx.doi.org/10.3762/bjoc.10.195 |
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