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Spatial Heterogeneity and Peptide Availability Determine CTL Killing Efficiency In Vivo

The rate at which a cytotoxic T lymphocyte (CTL) can survey for infected cells is a key ingredient of models of vertebrate immune responses to intracellular pathogens. Estimates have been obtained using in vivo cytotoxicity assays in which peptide-pulsed splenocytes are killed by CTL in the spleens...

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Detalles Bibliográficos
Autores principales:	Hogan, Thea, Kadolsky, Ulrich, Tung, Sim, Seddon, Benedict, Yates, Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168979/ https://www.ncbi.nlm.nih.gov/pubmed/25233372 http://dx.doi.org/10.1371/journal.pcbi.1003805

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