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NESmapper: Accurate Prediction of Leucine-Rich Nuclear Export Signals Using Activity-Based Profiles

The nuclear export of proteins is regulated largely through the exportin/CRM1 pathway, which involves the specific recognition of leucine-rich nuclear export signals (NESs) in the cargo proteins, and modulates nuclear–cytoplasmic protein shuttling by antagonizing the nuclear import activity mediated...

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Detalles Bibliográficos
Autores principales: Kosugi, Shunichi, Yanagawa, Hiroshi, Terauchi, Ryohei, Tabata, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168985/
https://www.ncbi.nlm.nih.gov/pubmed/25233087
http://dx.doi.org/10.1371/journal.pcbi.1003841