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Rapid and multi-level characterization of trastuzumab using sheathless capillary electrophoresis-tandem mass spectrometry
Monoclonal antibodies (mAbs) are highly complex proteins that display a wide range of microheterogeneity that requires multiple analytical methods for full structure assessment and quality control. As a consequence, the characterization of mAbs on different levels is particularly product - and time...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169039/ https://www.ncbi.nlm.nih.gov/pubmed/23563524 http://dx.doi.org/10.4161/mabs.23995 |