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Ribosome Rescue and Translation Termination at Non-Standard Stop Codons by ICT1 in Mammalian Mitochondria

Release factors (RFs) govern the termination phase of protein synthesis. Human mitochondria harbor four different members of the class 1 RF family: RF1Lmt/mtRF1a, RF1mt, C12orf65 and ICT1. The homolog of the essential ICT1 factor is widely distributed in bacteria and organelles and has the peculiar...

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Detalles Bibliográficos
Autores principales: Akabane, Shiori, Ueda, Takuya, Nierhaus, Knud H., Takeuchi, Nono
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169044/
https://www.ncbi.nlm.nih.gov/pubmed/25233460
http://dx.doi.org/10.1371/journal.pgen.1004616