Cargando…
How Much of the Variation in the Mutation Rate Along the Human Genome Can Be Explained?
It has been claimed recently that it may be possible to predict the rate of de novo mutation of each site in the human genome with a high degree of accuracy [Michaelson et al. (2012), Cell 151: 1431−1442]. We show that this claim is unwarranted. By considering the correlation between the rate of de...
Autores principales: | Eyre-Walker, Adam, Eyre-Walker, Ying Chen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169158/ https://www.ncbi.nlm.nih.gov/pubmed/24996580 http://dx.doi.org/10.1534/g3.114.012849 |
Ejemplares similares
-
The Role of Mutation Rate Variation and Genetic Diversity in the Architecture of Human Disease
por: Eyre-Walker, Ying Chen, et al.
Publicado: (2014) -
Cryptic Variation in the Human Mutation Rate
por: Hodgkinson, Alan, et al.
Publicado: (2009) -
Impact of Mutation Rate and Selection at Linked Sites on DNA Variation across the Genomes of Humans and Other Homininae
por: Castellano, David, et al.
Publicado: (2019) -
Investigating Evolutionary Rate Variation in Bacteria
por: Gibson, Beth, et al.
Publicado: (2019) -
Large scale variation in the rate of germ-line de novo mutation, base composition, divergence and diversity in humans
por: Smith, Thomas C. A., et al.
Publicado: (2018)