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Regulatory domain of troponin moves dynamically during activation of cardiac muscle

Heart muscle is activated by Ca(2+) to generate force and shortening, and the signaling pathway involves allosteric mechanisms in the thin filament. Knowledge about the structure-function relationship among proteins in the thin filament is critical in understanding the physiology and pathology of th...

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Detalles Bibliográficos
Autores principales: Sevrieva, Ivanka, Knowles, Andrea C., Kampourakis, Thomas, Sun, Yin-Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169182/
https://www.ncbi.nlm.nih.gov/pubmed/25101951
http://dx.doi.org/10.1016/j.yjmcc.2014.07.015