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Regulatory domain of troponin moves dynamically during activation of cardiac muscle
Heart muscle is activated by Ca(2+) to generate force and shortening, and the signaling pathway involves allosteric mechanisms in the thin filament. Knowledge about the structure-function relationship among proteins in the thin filament is critical in understanding the physiology and pathology of th...
Autores principales: | Sevrieva, Ivanka, Knowles, Andrea C., Kampourakis, Thomas, Sun, Yin-Biao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169182/ https://www.ncbi.nlm.nih.gov/pubmed/25101951 http://dx.doi.org/10.1016/j.yjmcc.2014.07.015 |
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