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Importance of extended protease substrate recognition motifs in steering BNIP-2 cleavage by human and mouse granzymes B

BACKGROUND: Previous screening of the substrate repertoires and substrate specificity profiles of granzymes resulted in long substrate lists highly likely containing bystander substrates. Here, a recently developed degradomics technology that allows distinguishing efficiently from less efficiently c...

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Detalles Bibliográficos
Autores principales:	Van Damme, Petra, Plasman, Kim, Vandemoortele, Giel, Jonckheere, Veronique, Maurer-Stroh, Sebastian, Gevaert, Kris
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169252/ https://www.ncbi.nlm.nih.gov/pubmed/25208769 http://dx.doi.org/10.1186/1471-2091-15-21

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