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MET Gene Copy Number Predicts Worse Overall Survival in Patients with Non-Small Cell Lung Cancer (NSCLC); A Systematic Review and Meta-Analysis

OBJECTIVES: MET is a receptor present in the membrane of NSCLC cells and is known to promote cell proliferation, survival and migration. MET gene copy number is a common genetic alteration and inhibition o MET emerges as a promising targeted therapy in NSCLC. Here we aim to combine in a meta-analysi...

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Detalles Bibliográficos
Autores principales: Dimou, Anastasios, Non, Lemuel, Chae, Young Kwang, Tester, William J., Syrigos, Konstantinos N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169409/
https://www.ncbi.nlm.nih.gov/pubmed/25232729
http://dx.doi.org/10.1371/journal.pone.0107677