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Myocardial Fibrosis Induced by Exposure to Subclinical Lipopolysaccharide Is Associated with Decreased miR-29c and Enhanced NOX2 Expression in Mice

BACKGROUND: Exposure to subclinical levels of lipopolysaccharide (LPS) occurs commonly and is seemingly well tolerated. However, recurrent LPS exposure induces cardiac fibrosis over 2 to 3 months in a murine model, not mediated by the renin-angiotensin system. Subclinical LPS induces cardiac fibrosi...

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Detalles Bibliográficos
Autores principales: Lew, Wilbur Y. W., Bayna, Evelyn, Dalle Molle, Erminia, Contu, Riccardo, Condorelli, Gianluigi, Tang, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169435/
https://www.ncbi.nlm.nih.gov/pubmed/25233448
http://dx.doi.org/10.1371/journal.pone.0107556