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Avian Influenza A H7N9 Virus Induces Severe Pneumonia in Mice without Prior Adaptation and Responds to a Combination of Zanamivir and COX-2 Inhibitor

BACKGROUND: Human infection caused by the avian influenza A H7N9 virus has a case-fatality rate of over 30%. Systematic study of the pathogenesis of avian H7N9 isolate and effective therapeutic strategies are needed. METHODS: BALB/c mice were inoculated intranasally with an H7N9 virus isolated from...

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Detalles Bibliográficos
Autores principales:	Li, Can, Li, Chuangen, Zhang, Anna J. X., To, Kelvin K. W., Lee, Andrew C. Y., Zhu, Houshun, Wu, Hazel W. L., Chan, Jasper F. W., Chen, Honglin, Hung, Ivan F. N., Li, Lanjuan, Yuen, Kwok-Yung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169509/ https://www.ncbi.nlm.nih.gov/pubmed/25232731 http://dx.doi.org/10.1371/journal.pone.0107966

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