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No Beneficial Effect of General and Specific Anti-Inflammatory Therapies on Aortic Dilatation in Marfan Mice

AIMS: Patients with Marfan syndrome have an increased risk of life-threatening aortic complications, mostly preceded by aortic dilatation. In the FBN1 (C1039G/+) Marfan mouse model, losartan decreases aortic root dilatation. We recently confirmed this beneficial effect of losartan in adult patients...

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Detalles Bibliográficos
Autores principales:	Franken, Romy, Hibender, Stijntje, den Hartog, Alexander W., Radonic, Teodora, de Vries, Carlie J. M., Zwinderman, Aeilko H., Groenink, Maarten, Mulder, Barbara J. M., de Waard, Vivian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169510/ https://www.ncbi.nlm.nih.gov/pubmed/25238161 http://dx.doi.org/10.1371/journal.pone.0107221

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