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Dimethyl Sulfoxide Damages Mitochondrial Integrity and Membrane Potential in Cultured Astrocytes
Dimethyl sulfoxide (DMSO) is a polar organic solvent that is used to dissolve neuroprotective or neurotoxic agents in neuroscience research. However, DMSO itself also has pharmacological and pathological effects on the nervous system. Astrocytes play a central role in maintaining brain homeostasis,...
Autores principales: | Yuan, Chan, Gao, Junying, Guo, Jichao, Bai, Lei, Marshall, Charles, Cai, Zhiyou, Wang, Linmei, Xiao, Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169574/ https://www.ncbi.nlm.nih.gov/pubmed/25238609 http://dx.doi.org/10.1371/journal.pone.0107447 |
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