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Dual Activation of the Bile Acid Nuclear Receptor FXR and G-Protein-Coupled Receptor TGR5 Protects Mice against Atherosclerosis

Bile acid signaling is a critical regulator of glucose and energy metabolism, mainly through the nuclear receptor FXR and the G protein-coupled receptor TGR. The purpose of the present study was to investigate whether dual activation of FXR and TGR5 plays a significant role in the prevention of athe...

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Detalles Bibliográficos
Autores principales:	Miyazaki-Anzai, Shinobu, Masuda, Masashi, Levi, Moshe, Keenan, Audrey L., Miyazaki, Makoto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169583/ https://www.ncbi.nlm.nih.gov/pubmed/25237811 http://dx.doi.org/10.1371/journal.pone.0108270

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