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Structure based modification of Bluetongue virus helicase protein VP6 to produce a viable VP6-truncated BTV
Bluetongue virus core protein VP6 is an ATP hydrolysis dependent RNA helicase. However, despite much study, the precise role of VP6 within the viral capsid and its structure remain unclear. To investigate the requirement of VP6 in BTV replication, we initiated a structural and biological study. Mult...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169673/ https://www.ncbi.nlm.nih.gov/pubmed/25128829 http://dx.doi.org/10.1016/j.bbrc.2014.08.028 |