hNAG-1 increases lifespan by regulating energy metabolism and insulin/IGF-1/mTOR signaling

Nonsteroidal anti-inflammatory drug-activated gene (NAG-1) or GDF15 is a divergent member of the transforming growth factor beta (TGF-β) superfamily and mice expressing hNAG-1/hGDF15 have been shown to be resistant to HFD-induced obesity and inflammation. This study investigated if hNAG-1 increases...

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Detalles Bibliográficos
Autores principales: Wang, Xingya, Chrysovergis, Kali, Kosak, Justin, Kissling, Grace, Streicker, Mike, Moser, Glenda, Li, Ruifang, Eling, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169862/
https://www.ncbi.nlm.nih.gov/pubmed/25239873

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