Cargando…

A systematic review of the pathophysiology of 5-fluorouracil-induced cardiotoxicity

BACKGROUND: Cardiotoxicity is a serious side effect to treatment with 5-fluorouracil (5-FU), but the underlying mechanisms are not fully understood. The objective of this systematic review was to evaluate the pathophysiology of 5-FU- induced cardiotoxicity. METHODS: We systematically searched PubMed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Polk, Anne, Vistisen, Kirsten, Vaage-Nilsen, Merete, Nielsen, Dorte L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170068/ https://www.ncbi.nlm.nih.gov/pubmed/25186061 http://dx.doi.org/10.1186/2050-6511-15-47

Ejemplares similares

Incidence and risk factors for capecitabine-induced symptomatic cardiotoxicity: a retrospective study of 452 consecutive patients with metastatic breast cancer
por: Polk, Anne, et al.
Publicado: (2016)

5-fluorouracil and cardiotoxicity: a review
por: Sara, Jaskanwal D., et al.
Publicado: (2018)

Colchicine Ameliorates 5-Fluorouracil-Induced Cardiotoxicity in Rats
por: Safarpour, Soheila, et al.
Publicado: (2022)

5-Fluorouracil Rechallenge After Cardiotoxicity
por: Desai, Aakash, et al.
Publicado: (2020)

Cardiotoxicities of 5-Fluorouracil and Other Fluoropyrimidines
por: Shiga, Taro, et al.
Publicado: (2020)

5-Fluorouracil Cardiotoxicity: Known But Unknown
por: Brell, Joanna M.
Publicado: (2021)

Rare Presentation of Cardiotoxicity Related to 5-Fluorouracil
por: Charkviani, Mariam, et al.
Publicado: (2020)

5-Fluorouracil-related Cardiotoxicity with Coronary Vasospasms
por: Faheem, Beenish, et al.
Publicado: (2022)

Prophylactic options in patients with 5-fluorouracil-associated cardiotoxicity
por: Cianci, G, et al.
Publicado: (2003)

5-Fluorouracil-induced cardiotoxicity mimicking myocardial infarction: a case report
por: McGlinchey, Paul G, et al.
Publicado: (2001)

Protective Effect of Kaempferol and Its Nanoparticles on 5-Fluorouracil-Induced Cardiotoxicity in Rats
por: Safarpour, Soheila, et al.
Publicado: (2022)

Reintroduction of 5-Fluorouracil Post-cardiac Arrest Secondary to Chemotherapy-Induced Cardiotoxicity
por: Wu, Kathie, et al.
Publicado: (2023)

Myricetin (3,3′,4′,5,5′,7-Hexahydroxyflavone) Prevents 5-Fluorouracil-Induced Cardiotoxicity
por: Arafah, Azher, et al.
Publicado: (2022)

Chemotherapy-Induced Cardiotoxicity: Pathophysiology and Prevention
por: CSAPO, MELINDA, et al.
Publicado: (2014)

Cardioprotective potential of mitochondria-targeted antioxidant, mito-TEMPO, in 5-fluorouracil-induced cardiotoxicity
por: Tambe, Prasad Kisan, et al.
Publicado: (2023)

Cardiotoxicity of 5-fluorouracil and capecitabine in Chinese patients: a prospective study
por: Peng, Jianjun, et al.
Publicado: (2018)

Cardiotoxicity of commercial 5-fluorouracil vials stems from the alkaline hydrolysis of this drug.
por: Lemaire, L., et al.
Publicado: (1992)

Pathophysiology and preventive strategies of anthracycline-induced cardiotoxicity
por: Chung, Woo-Baek, et al.
Publicado: (2016)

Diagnosis and Management of a Patient With 5-Fluorouracil-Induced ST Elevation and Nonsustained Ventricular Tachycardia as a Late Presentation of Cardiotoxicity and Successful 5-Fluorouracil Rechallenge
por: Medepalli, Lalitha C, et al.
Publicado: (2022)

Indole Alkaloid Derivative B, a Novel Bifunctional Agent That Mitigates 5-Fluorouracil-Induced Cardiotoxicity
por: Bi, Wei, et al.
Publicado: (2018)

The Impact of Metformin on the Development of Hypothyroidism and Cardiotoxicity Induced by Cyclophosphamide, Methotrexate, and Fluorouracil in Rats
por: Alhowail, Ahmad H., et al.
Publicado: (2023)

Raltitrexed (Tomudex): an alternative drug for patients with colorectal cancer and 5-fluorouracil associated cardiotoxicity.
por: KÃ¶hne, C. H., et al.
Publicado: (1998)

Specific CDK4/6 inhibition in breast cancer: a systematic review of current clinical evidence
por: Polk, Anne, et al.
Publicado: (2017)

Early Manifestation of Clozapine-Induced Cardiotoxicity: Detection, Pathophysiology, and Management
por: Hamilton, Steven, et al.
Publicado: (2022)

Activated ROCK/Akt/eNOS and ET-1/ERK pathways in 5-fluorouracil-induced cardiotoxicity: modulation by simvastatin
por: Muhammad, Radwa Nasser, et al.
Publicado: (2020)

Molecular insights into the pathophysiology of doxorubicin-induced cardiotoxicity: a graphical representation
por: Sangweni, Nonhlakanipho F., et al.
Publicado: (2022)

Wnt5a expression and prognosis in stage II–III colon cancer
por: Lund, Cecilia Margareta, et al.
Publicado: (2020)

Doxorubicin Is Key for the Cardiotoxicity of FAC (5-Fluorouracil + Adriamycin + Cyclophosphamide) Combination in Differentiated H9c2 Cells
por: Pereira-Oliveira, Maria, et al.
Publicado: (2019)

The use of 5‐fluorouracil in the prevention of tendon adhesions: A systematic review
por: Nazifi, Omid, et al.
Publicado: (2020)

5-FU induced cardiotoxicity: case series and review of the literature
por: Yuan, Cai, et al.
Publicado: (2019)

Abnormal Dihydropyrimidine Dehydrogenase Activity as an Indicator of Potential 5-Fluorouracil Linked Cardiotoxicity in Colorectal Cancer Patients: Are Toxic Events Inevitable?
por: Chakwop Ngassa, Hyginus, et al.
Publicado: (2021)

A systematic review of the cardiotoxicity of methadone
por: Alinejad, Samira, et al.
Publicado: (2015)

5-Fluorouracil-induced vasospastic angina
por: Ayyildiz, Orhan, et al.
Publicado: (2005)

Fluorouracil (5-FU)-induced Cardiomyopathy
por: Thalambedu, Nishanth, et al.
Publicado: (2019)

5-Fluorouracil–Induced Coronary Vasospasm
por: Arya, Sumedha, et al.
Publicado: (2018)

Docetaxel, cisplatin, and 5-fluorouracil compared with epirubicin, cisplatin, and 5-fluorouracil regimen for advanced gastric cancer: A systematic review and meta-analysis
por: Li, Bo, et al.
Publicado: (2019)

Hypertensive Cardiotoxicity in Cancer Treatment—Systematic Analysis of Adjunct, Conventional Chemotherapy, and Novel Therapies—Epidemiology, Incidence, and Pathophysiology
por: Chung, Robin, et al.
Publicado: (2020)

Protective Role of Enalapril in Anthracycline-Induced Cardiotoxicity: A Systematic Review
por: Zhang, Yili, et al.
Publicado: (2020)

Acute, severe and anaphylactoid reactions are very rare with low-molecular-weight iron dextran, CosmoFer®
por: Vaage-Nilsen, Odd
Publicado: (2008)

Comment on: Tam et al. Defining Insulin Resistance From Hyperinsulinemic-Euglycemic Clamps. Diabetes Care 2012;35:1605–1610
por: Færch, Kristine, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_da0ccqjqm76bfcbjpdhmcjknbn