Factors and Mechanisms Involved in the Coupling from Bone Resorption to Formation: How Osteoclasts Talk to Osteoblasts

Bone remodeling is the fundamental means by which the quality as well as quantity of the skeleton is maintained throughout adult life. When bone remodeling goes awry, a metabolic bone disease such as osteoporosis ensues. Among multiple phases of the complex remodeling process, we focus in this revie...

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Detalles Bibliográficos
Autores principales: Ikeda, Kyoji, Takeshita, Sunao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Bone and Mineral Research 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170079/
https://www.ncbi.nlm.nih.gov/pubmed/25247154
http://dx.doi.org/10.11005/jbm.2014.21.3.163
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author Ikeda, Kyoji
Takeshita, Sunao
author_facet Ikeda, Kyoji
Takeshita, Sunao
author_sort Ikeda, Kyoji
collection PubMed
description Bone remodeling is the fundamental means by which the quality as well as quantity of the skeleton is maintained throughout adult life. When bone remodeling goes awry, a metabolic bone disease such as osteoporosis ensues. Among multiple phases of the complex remodeling process, we focus in this review on factors and mechanisms that are involved in the coupling of bone formation to preceding resorption.
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spelling pubmed-41700792014-09-22 Factors and Mechanisms Involved in the Coupling from Bone Resorption to Formation: How Osteoclasts Talk to Osteoblasts Ikeda, Kyoji Takeshita, Sunao J Bone Metab Review Article Bone remodeling is the fundamental means by which the quality as well as quantity of the skeleton is maintained throughout adult life. When bone remodeling goes awry, a metabolic bone disease such as osteoporosis ensues. Among multiple phases of the complex remodeling process, we focus in this review on factors and mechanisms that are involved in the coupling of bone formation to preceding resorption. The Korean Society for Bone and Mineral Research 2014-08 2014-08-31 /pmc/articles/PMC4170079/ /pubmed/25247154 http://dx.doi.org/10.11005/jbm.2014.21.3.163 Text en Copyright © 2014 The Korean Society for Bone and Mineral Research http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Ikeda, Kyoji
Takeshita, Sunao
Factors and Mechanisms Involved in the Coupling from Bone Resorption to Formation: How Osteoclasts Talk to Osteoblasts
title Factors and Mechanisms Involved in the Coupling from Bone Resorption to Formation: How Osteoclasts Talk to Osteoblasts
title_full Factors and Mechanisms Involved in the Coupling from Bone Resorption to Formation: How Osteoclasts Talk to Osteoblasts
title_fullStr Factors and Mechanisms Involved in the Coupling from Bone Resorption to Formation: How Osteoclasts Talk to Osteoblasts
title_full_unstemmed Factors and Mechanisms Involved in the Coupling from Bone Resorption to Formation: How Osteoclasts Talk to Osteoblasts
title_short Factors and Mechanisms Involved in the Coupling from Bone Resorption to Formation: How Osteoclasts Talk to Osteoblasts
title_sort factors and mechanisms involved in the coupling from bone resorption to formation: how osteoclasts talk to osteoblasts
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170079/
https://www.ncbi.nlm.nih.gov/pubmed/25247154
http://dx.doi.org/10.11005/jbm.2014.21.3.163
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