Microarray Analysis of Gene Expression Reveals that Cyclo-oxygenase-2 Gene Therapy Up-regulates Hematopoiesis and Down-regulates Inflammation During Endochondral Bone Fracture Healing

BACKGROUND: Cyclo-oxygenase-2 (Cox-2) is an inflammatory mediator that is necessary for the tissue repair, including bone fracture healing. Although the application of Cox-2 gene therapy to a murine closed femoral fracture has accelerated bony union, but the beneficial effect was not observed until...

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Detalles Bibliográficos
Autores principales: Lau, K.-H. William, Popa, Nicoleta L., Rundle, Charles H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Bone and Mineral Research 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170080/
https://www.ncbi.nlm.nih.gov/pubmed/25247155
http://dx.doi.org/10.11005/jbm.2014.21.3.169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170080/
https://www.ncbi.nlm.nih.gov/pubmed/25247155
http://dx.doi.org/10.11005/jbm.2014.21.3.169

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