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Nucleus-targeted Dmp1 transgene fails to rescue dental defects in Dmp1 null mice

Dentin matrix protein 1 (DMP1) is essential to odontogenesis. Its mutations in human subjects lead to dental problems such as dental deformities, hypomineralization and periodontal impairment. Primarily, DMP1 is considered as an extracellular matrix protein that promotes hydroxyapatite formation and...

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Detalles Bibliográficos
Autores principales:	Lin, Shu-Xian, Zhang, Qi, Zhang, Hua, Yan, Kevin, Ward, Leanne, Lu, Yong-Bo, Feng, Jian-Quan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170153/ https://www.ncbi.nlm.nih.gov/pubmed/25105818 http://dx.doi.org/10.1038/ijos.2014.44

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