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The scaffold protein Nde1 safeguards the brain genome during S phase of early neural progenitor differentiation
Successfully completing the S phase of each cell cycle ensures genome integrity. Impediment of DNA replication can lead to DNA damage and genomic disorders. In this study, we show a novel function for NDE1, whose mutations cause brain developmental disorders, in safeguarding the genome through S pha...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170211/ https://www.ncbi.nlm.nih.gov/pubmed/25245017 http://dx.doi.org/10.7554/eLife.03297 |