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Pediatric liquid medicaments – Are they cariogenic? An in vitro study

AIM: Young and chronically sick children receive a variety of oral liquid medications on a routine and regular basis. These pharmaceutical preparations are cariogenic and acidogenic in nature. Hence, the present study was taken up to determine the cariogenic potential of the commonly prescribed pedi...

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Autores principales: Babu, K. L. Girish, Doddamani, Geeta Maruti, Naik, L. R. Kumaraswamy, Jagadeesh, K. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170542/
https://www.ncbi.nlm.nih.gov/pubmed/25254195
http://dx.doi.org/10.4103/2231-0762.137637
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author Babu, K. L. Girish
Doddamani, Geeta Maruti
Naik, L. R. Kumaraswamy
Jagadeesh, K. N.
author_facet Babu, K. L. Girish
Doddamani, Geeta Maruti
Naik, L. R. Kumaraswamy
Jagadeesh, K. N.
author_sort Babu, K. L. Girish
collection PubMed
description AIM: Young and chronically sick children receive a variety of oral liquid medications on a routine and regular basis. These pharmaceutical preparations are cariogenic and acidogenic in nature. Hence, the present study was taken up to determine the cariogenic potential of the commonly prescribed pediatric liquid medicaments. MATERIALS AND METHODS: Eight commonly used pediatric liquid medicaments (PLM) were selected and their endogenous pH was measured using a pH electrode meter. The sugar content in them was estimated using High Performance Liquid Chromatography (HPLC). The effect of PLM on Streptococcus mutans was assessed by the ditch plate method. RESULTS: The pH of the liquid medicaments ranged between 6.05 (Salbid(®)) and 7.71 (Theopid(®)). Sucrose was observed in 7 PLM and glucose in 5 PLM. The highest concentration of sucrose was seen in Crocin(®). The lowest concentration of sucrose was seen with Althrocin(®). Both the antibiotic PLMs inhibited the S. mutans growth. Zevit(®) promoted the growth of S. mutans. CONCLUSION: The pH and concentration of sugars of pediatric liquid medicaments can pose as a threat to dental health, especially in chronically sick children, who are on long-term medications.
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spelling pubmed-41705422014-09-24 Pediatric liquid medicaments – Are they cariogenic? An in vitro study Babu, K. L. Girish Doddamani, Geeta Maruti Naik, L. R. Kumaraswamy Jagadeesh, K. N. J Int Soc Prev Community Dent Original Article AIM: Young and chronically sick children receive a variety of oral liquid medications on a routine and regular basis. These pharmaceutical preparations are cariogenic and acidogenic in nature. Hence, the present study was taken up to determine the cariogenic potential of the commonly prescribed pediatric liquid medicaments. MATERIALS AND METHODS: Eight commonly used pediatric liquid medicaments (PLM) were selected and their endogenous pH was measured using a pH electrode meter. The sugar content in them was estimated using High Performance Liquid Chromatography (HPLC). The effect of PLM on Streptococcus mutans was assessed by the ditch plate method. RESULTS: The pH of the liquid medicaments ranged between 6.05 (Salbid(®)) and 7.71 (Theopid(®)). Sucrose was observed in 7 PLM and glucose in 5 PLM. The highest concentration of sucrose was seen in Crocin(®). The lowest concentration of sucrose was seen with Althrocin(®). Both the antibiotic PLMs inhibited the S. mutans growth. Zevit(®) promoted the growth of S. mutans. CONCLUSION: The pH and concentration of sugars of pediatric liquid medicaments can pose as a threat to dental health, especially in chronically sick children, who are on long-term medications. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4170542/ /pubmed/25254195 http://dx.doi.org/10.4103/2231-0762.137637 Text en Copyright: © Journal of International Society of Preventive and Community Dentistry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Babu, K. L. Girish
Doddamani, Geeta Maruti
Naik, L. R. Kumaraswamy
Jagadeesh, K. N.
Pediatric liquid medicaments – Are they cariogenic? An in vitro study
title Pediatric liquid medicaments – Are they cariogenic? An in vitro study
title_full Pediatric liquid medicaments – Are they cariogenic? An in vitro study
title_fullStr Pediatric liquid medicaments – Are they cariogenic? An in vitro study
title_full_unstemmed Pediatric liquid medicaments – Are they cariogenic? An in vitro study
title_short Pediatric liquid medicaments – Are they cariogenic? An in vitro study
title_sort pediatric liquid medicaments – are they cariogenic? an in vitro study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170542/
https://www.ncbi.nlm.nih.gov/pubmed/25254195
http://dx.doi.org/10.4103/2231-0762.137637
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