Cargando…

A nucleolin-DNMT1 regulatory axis in acute myeloid leukemogenesis

Nucleolin overexpression and DNA hypermethylation have been implicated in cancer pathogenesis, but whether and how these aberrations cooperate in controlling leukemia cell fate remain elusive. Here, we provide the first mechanistic insights into the role of nucleolin in leukemogenesis through creati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shen, Na, Yan, Fei, Pang, Jiuxia, Wu, Lai-Chu, Al-Kali, Aref, Litzow, Mark R., Liu, Shujun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170608/ https://www.ncbi.nlm.nih.gov/pubmed/25015109

Ejemplares similares

Liposomal bortezomib is active against chronic myeloid leukemia by disrupting the Sp1-BCR/ABL axis
por: Yang, Xiaojuan, et al.
Publicado: (2016)

A dynamic N(6)-methyladenosine methylome regulates intrinsic and acquired resistance to tyrosine kinase inhibitors
por: Yan, Fei, et al.
Publicado: (2018)

A novel miR-375-HOXB3-CDCA3/DNMT3B regulatory circuitry contributes to leukemogenesis in acute myeloid leukemia
por: Bi, Laixi, et al.
Publicado: (2018)

Editorial: Mechanisms of Epigenetics and Genetics in Leukemogenesis
por: Li, Yonghui, et al.
Publicado: (2022)

RAF Kinase Inhibitor Protein in Myeloid Leukemogenesis
por: Zebisch, Armin, et al.
Publicado: (2019)

A regulatory circuit composed of DNA methyltransferases and receptor tyrosine kinases controls lung cancer cell aggressiveness
por: Yan, Fei, et al.
Publicado: (2017)

DNMT3A Mutation-Induced CDK1 Overexpression Promotes Leukemogenesis by Modulating the Interaction between EZH2 and DNMT3A
por: Yang, Ying, et al.
Publicado: (2021)

Mechanisms of myeloid leukemogenesis: Current perspectives and therapeutic objectives
por: Bouligny, Ian M., et al.
Publicado: (2023)

The mutual regulatory loop between TPTEP1 and miR-1303 in leukemogenesis of acute myeloid leukemia
por: Li, Li, et al.
Publicado: (2021)

Methylation-associated silencing of BASP1 contributes to leukemogenesis in t(8;21) acute myeloid leukemia
por: Zhou, Lei, et al.
Publicado: (2018)

Dnmt3a deletion cooperates with the Flt3/ITD mutation to drive leukemogenesis in a murine model
por: Poitras, Jennifer L., et al.
Publicado: (2016)

Role of Nucleophosmin Gene Mutation in Leukemogenesis of Acute Myeloid Leukemia
por: Khaled, Safaa A.A., et al.
Publicado: (2018)

P456: LEUKEMOGENESIS BY AML-SPECIFIC DRIVER MUTATIONS WITHIN DNMT3A, IDH2 AND NPM1
por: Mehmetbeyoglu, Ecmel, et al.
Publicado: (2023)

The Philadelphia chromosome in leukemogenesis
por: Kang, Zhi-Jie, et al.
Publicado: (2016)

Hepatoma-derived growth factor/nucleolin axis as a novel oncogenic pathway in liver carcinogenesis
por: Chen, San-Cher, et al.
Publicado: (2015)

The process of leukemogenesis.
por: Irons, R D, et al.
Publicado: (1996)

Mosaic loss of chromosome Y promotes leukemogenesis and clonal hematopoiesis
por: Zhang, Qi, et al.
Publicado: (2022)

Clinical Implication of DNMT3A and TET2 Genes Mutations in Cytogenetically Normal Acute Myeloid Leukemia
por: Aref, Salah, et al.
Publicado: (2022)

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia
por: Zhu, Xiao-Na, et al.
Publicado: (2023)

The Possible Importance of β3 Integrins for Leukemogenesis and Chemoresistance in Acute Myeloid Leukemia
por: Johansen, Silje, et al.
Publicado: (2018)

Tet1 is not required for myeloid leukemogenesis by MLL-ENL in novel mouse models
por: Ono, Ryoichi, et al.
Publicado: (2021)

Protein lysine 43 methylation by EZH1 promotes AML1-ETO transcriptional repression in leukemia
por: Dou, Liping, et al.
Publicado: (2019)

Oncogenic Roles and Inhibitors of DNMT1, DNMT3A, and DNMT3B in Acute Myeloid Leukaemia
por: Wong, Kah Keng, et al.
Publicado: (2019)

Aberrant Mer receptor tyrosine kinase expression contributes to leukemogenesis in acute myeloid leukemia
por: Lee-Sherick, A B, et al.
Publicado: (2013)

The PIM family of oncoproteins: Small kinases with huge implications in myeloid leukemogenesis and as therapeutic targets
por: Saurabh, Kumar, et al.
Publicado: (2014)

H19 overexpression promotes leukemogenesis and predicts unfavorable prognosis in acute myeloid leukemia
por: Zhang, Ting-juan, et al.
Publicado: (2018)

RUNX1 mutations promote leukemogenesis of myeloid malignancies in ASXL1-mutated leukemia
por: Bera, Rabindranath, et al.
Publicado: (2019)

Toll-like Receptor 4, Osteoblasts and Leukemogenesis; the Lesson from Acute Myeloid Leukemia
por: Bruserud, Øystein, et al.
Publicado: (2022)

Epigenetic silencing of UBXN8 contributes to leukemogenesis in t(8;21) acute myeloid leukemia
por: Yang, Erna, et al.
Publicado: (2021)

BCL11A promotes myeloid leukemogenesis by repressing PU.1 target genes
por: Sunami, Yoshitaka, et al.
Publicado: (2022)

Functional association of NR4A3 downregulation with impaired differentiation in myeloid leukemogenesis
por: Lin, Shih-Chiang, et al.
Publicado: (2022)

Nucleolin promotes angiogenesis and endothelial metabolism along the oncofetal axis in the human brain vasculature
por: Schwab, Marc, et al.
Publicado: (2023)

Thymoquinone exerts potent growth-suppressive activity on leukemia through DNA hypermethylation reversal in leukemia cells
por: Pang, Jiuxia, et al.
Publicado: (2017)

Cooperation of Dnmt3a R878H with Nras G12D promotes leukemogenesis in knock-in mice: a pilot study
por: Shi, Xiaodong, et al.
Publicado: (2019)

Outcomes of allogeneic transplant in patients with DDX41 mutated myelodysplastic syndrome and acute myeloid leukemia
por: Baranwal, Anmol, et al.
Publicado: (2022)

Molecular predictors of response to venetoclax plus hypomethylating agent in treatment-naïve acute myeloid leukemia
por: Gangat, Naseema, et al.
Publicado: (2022)

A vicious loop of fatty acid-binding protein 4 and DNA methyltransferase 1 promotes acute myeloid leukemia and acts as a therapeutic target
por: Yan, F, et al.
Publicado: (2017)

AS1411 Nucleolin-Specific Binding Aptamers Reduce Pathological Angiogenesis through Inhibition of Nucleolin Phosphorylation
por: Iturriaga-Goyon, Emilio, et al.
Publicado: (2021)

Depletion of Ars2 inhibits cell proliferation and leukemogenesis in acute myeloid leukemia by modulating the miR-6734-3p/p27 axis
por: Hu, Xiaoye, et al.
Publicado: (2018)

Elevated Cellular PD1/PD-L1 Expression Confers Acquired Resistance to Cisplatin in Small Cell Lung Cancer Cells
por: Yan, Fei, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_2d47r7kgmf4pgovcrnr20e6hju