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Specific delivery of microRNA93 into HBV-replicating hepatocytes downregulates protein expression of liver cancer susceptible gene MICA
Chronic hepatitis B virus (HBV) infection is a major cause of hepatocellular carcinoma (HCC). To date, the lack of efficient in vitro systems supporting HBV infection and replication has been a major limitation of HBV research. Although primary human hepatocytes support the complete HBV life cycle,...
Autores principales: | Ohno, Motoko, Otsuka, Motoyuki, Kishikawa, Takahiro, Shibata, Chikako, Yoshikawa, Takeshi, Takata, Akemi, Muroyama, Ryosuke, Kowatari, Norie, Sato, Masaya, Kato, Naoya, Kuroda, Shun'ichi, Koike, Kazuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170619/ https://www.ncbi.nlm.nih.gov/pubmed/25026299 |
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