Macrophages are recruited to hypoxic tumor areas and acquire a Pro-Angiogenic M2-Polarized phenotype via hypoxic cancer cell derived cytokines Oncostatin M and Eotaxin

TAMs, a unique and distinct M2-skewed myeloid population of tumor stroma, exhibiting pro-tumor functions is fast emerging as a potential target for anti-cancer immunotherapy. Macrophage-recruitment and M2-polarization represent key TAMs-related phenomenon that are amenable to therapeutic interventio...

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Detalles Bibliográficos
Autores principales: Tripathi, Chakrapani, Tewari, Brij Nath, Kanchan, Ranjana Kumari, Baghel, Khemraj Singh, Nautiyal, Naveen, Shrivastava, Richa, Kaur, Harbeer, Bhatt, Madan Lal Bramha, Bhadauria, Smrati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170629/
https://www.ncbi.nlm.nih.gov/pubmed/25051364

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