MiR-143 acts as a tumor suppressor by targeting N-RAS and enhances temozolomide-induced apoptosis in glioma

Therapeutic applications of microRNAs (miRNAs) in RAS-driven glioma were valuable, but their specific roles and functions have yet to be fully elucidated. Here, we firstly report that miR-143 directly targets the neuroblastoma RAS viral oncogene homolog (N-RAS) and functions as a tumor-suppressor in...

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Detalles Bibliográficos
Autores principales: Wang, Lin, Shi, Zhu-mei, Jiang, Cheng-fei, Liu, Xue, Chen, Qiu-dan, Qian, Xu, Li, Dong-mei, Ge, Xin, Wang, Xie-feng, Liu, Ling-Zhi, You, Yong-ping, Liu, Ning, Jiang, Bing-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170647/
https://www.ncbi.nlm.nih.gov/pubmed/24980823

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