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Type I IFN Induces IL-10 Production in an IL-27–Independent Manner and Blocks Responsiveness to IFN-γ for Production of IL-12 and Bacterial Killing in Mycobacterium tuberculosis–Infected Macrophages

Tuberculosis, caused by the intracellular bacterium Mycobacterium tuberculosis, currently causes ∼1.4 million deaths per year, and it therefore remains a leading global health problem. The immune response during tuberculosis remains incompletely understood, particularly regarding immune factors that...

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Detalles Bibliográficos
Autores principales:	McNab, Finlay W., Ewbank, John, Howes, Ashleigh, Moreira-Teixeira, Lucia, Martirosyan, Anna, Ghilardi, Nico, Saraiva, Margarida, O’Garra, Anne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2014
Materias:	Infectious Disease and Host Response
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170673/ https://www.ncbi.nlm.nih.gov/pubmed/25187652 http://dx.doi.org/10.4049/jimmunol.1401088

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