TLR-Mediated Inflammatory Responses to Streptococcus pneumoniae Are Highly Dependent on Surface Expression of Bacterial Lipoproteins

Streptococcus pneumoniae infections induce inflammatory responses that contribute toward both disease pathogenesis and immunity, but the host–pathogen interactions that mediate these effects are poorly defined. We used the surface lipoprotein-deficient ∆lgt pneumococcal mutant strain to test the hyp...

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Detalles Bibliográficos
Autores principales: Tomlinson, Gillian, Chimalapati, Suneeta, Pollard, Tracey, Lapp, Thabo, Cohen, Jonathan, Camberlein, Emilie, Stafford, Sian, Periselneris, Jimstan, Aldridge, Christine, Vollmer, Waldemar, Picard, Capucine, Casanova, Jean-Laurent, Noursadeghi, Mahdad, Brown, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2014
Materias:
Innate Immunity and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170674/
https://www.ncbi.nlm.nih.gov/pubmed/25172490
http://dx.doi.org/10.4049/jimmunol.1401413

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