Human stem cell models of dementia

Positive predictions were made in the aftermath of the development of induced pluripotent stem cell technology for the use of patient-specific iPSCs to model neurological diseases, including dementia. Here, we review the current state of the field and explore how close we are to the goal of in vitro...

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Detalles Bibliográficos
Autor principal: Livesey, Frederick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170721/
https://www.ncbi.nlm.nih.gov/pubmed/24939911
http://dx.doi.org/10.1093/hmg/ddu302
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author Livesey, Frederick J.
author_facet Livesey, Frederick J.
author_sort Livesey, Frederick J.
collection PubMed
description Positive predictions were made in the aftermath of the development of induced pluripotent stem cell technology for the use of patient-specific iPSCs to model neurological diseases, including dementia. Here, we review the current state of the field and explore how close we are to the goal of in vitro models that capture all aspects of the cell and molecular biology of dementia.
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spelling pubmed-41707212014-09-22 Human stem cell models of dementia Livesey, Frederick J. Hum Mol Genet Articles Positive predictions were made in the aftermath of the development of induced pluripotent stem cell technology for the use of patient-specific iPSCs to model neurological diseases, including dementia. Here, we review the current state of the field and explore how close we are to the goal of in vitro models that capture all aspects of the cell and molecular biology of dementia. Oxford University Press 2014-09-15 2014-06-16 /pmc/articles/PMC4170721/ /pubmed/24939911 http://dx.doi.org/10.1093/hmg/ddu302 Text en © The Author 2014. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Livesey, Frederick J.
Human stem cell models of dementia
title Human stem cell models of dementia
title_full Human stem cell models of dementia
title_fullStr Human stem cell models of dementia
title_full_unstemmed Human stem cell models of dementia
title_short Human stem cell models of dementia
title_sort human stem cell models of dementia
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170721/
https://www.ncbi.nlm.nih.gov/pubmed/24939911
http://dx.doi.org/10.1093/hmg/ddu302
work_keys_str_mv AT liveseyfrederickj humanstemcellmodelsofdementia

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