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Modeling, Molecular Dynamics Simulation, and Mutation Validation for Structure of Cannabinoid Receptor 2 Based on Known Crystal Structures of GPCRs
[Image: see text] The cannabinoid receptor 2 (CB2) plays an important role in the immune system. Although a few of GPCRs crystallographic structures have been reported, it is still challenging to obtain functional transmembrane proteins and high resolution X-ray crystal structures, such as for the C...
Autores principales: | Feng, Zhiwei, Alqarni, Mohammed Hamed, Yang, Peng, Tong, Qin, Chowdhury, Ananda, Wang, Lirong, Xie, Xiang-Qun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170816/ https://www.ncbi.nlm.nih.gov/pubmed/25141027 http://dx.doi.org/10.1021/ci5002718 |
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