Cargando…

Nucleotides Regulate Secretion of the Inflammatory Chemokine CCL2 from Human Macrophages and Monocytes

CCL2 is an important inflammatory chemokine involved in monocyte recruitment to inflamed tissues. The extracellular nucleotide signalling molecules UTP and ATP acting via the P2Y2 receptor are known to induce CCL2 secretion in macrophages. We confirmed this in the human THP-1 monocytic cell line sho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Higgins, K. R., Kovacevic, W., Stokes, L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170906/ https://www.ncbi.nlm.nih.gov/pubmed/25276053 http://dx.doi.org/10.1155/2014/293925

Ejemplares similares

Intestinal CD169(+) macrophages initiate mucosal inflammation by secreting CCL8 that recruits inflammatory monocytes
por: Asano, Kenichi, et al.
Publicado: (2015)

Macrophage derived chemokine (CCL22), thymus and activation-regulated chemokine (CCL17), and CCR4 in idiopathic pulmonary fibrosis
por: Yogo, Yurika, et al.
Publicado: (2009)

Monocytes/macrophages express chemokine receptor CCR9 in rheumatoid arthritis and CCL25 stimulates their differentiation
por: Schmutz, Caroline, et al.
Publicado: (2010)

Breast Cancer: Coordinated Regulation of CCL2 Secretion by Intracellular Glycosaminoglycans and Chemokine Motifs()()
por: Lebel-Haziv, Yaeli, et al.
Publicado: (2014)

Chemokines (CCL3, CCL4, and CCL5) Inhibit ATP-Induced Release of IL-1β by Monocytic Cells
por: Amati, Anca-Laura, et al.
Publicado: (2017)

The Inflammatory Chemokine CCL5 and Cancer Progression
por: Aldinucci, Donatella, et al.
Publicado: (2014)

The Intestinal Chemokine Thymus-expressed Chemokine (CCL25) Attracts IgA Antibody-secreting Cells
por: Bowman, Edward P., et al.
Publicado: (2002)

The chemokine monocyte chemoattractant protein-1/CCL2 is a promoter of breast cancer metastasis
por: Yoshimura, Teizo, et al.
Publicado: (2023)

Pro-Inflammatory Chemokine CCL2 (MCP-1) Promotes Healing in Diabetic Wounds by Restoring the Macrophage Response
por: Wood, Stephen, et al.
Publicado: (2014)

Macrophage-derived chemokine CCL22 and regulatory T cells in ovarian cancer patients
por: Wertel, I., et al.
Publicado: (2015)

Revisiting CCL-type chemokines in breast cancer and its milieu: prominent targetable chemokines, CCL8 and CCL21
por: Unver, Nese
Publicado: (2021)

CC chemokines CCL2, CCL3, CCL4 and CCL5 are elevated in osteoporosis patients
por: Farangis, Fatehi, et al.
Publicado: (2017)

Effects of the mTOR inhibitor Rapamycin on Monocyte-Secreted Chemokines
por: Lin, Hugo You-Hsien, et al.
Publicado: (2014)

Mechanism of Macrophage-Derived Chemokine/CCL22 Production by HaCaT Keratinocytes
por: Yano, Chizuko, et al.
Publicado: (2015)

Macrophage-Derived Chemokine MDC/CCL22: An Ambiguous Finding in COVID-19
por: Korobova, Zoia R., et al.
Publicado: (2023)

CCL2 recruits inflammatory monocytes to facilitate breast tumor metastasis
por: Qian, Bin-Zhi, et al.
Publicado: (2011)

Inhibition of CCL2 by bindarit alleviates diabetes-associated periodontitis by suppressing inflammatory monocyte infiltration and altering macrophage properties
por: Shen, Zongshan, et al.
Publicado: (2020)

SARS-CoV-2 Infected Cardiomyocytes Recruit Monocytes by Secreting CCL2
por: Chen, Shuibing, et al.
Publicado: (2020)

Sinomenine Inhibits the Progression of Rheumatoid Arthritis by Regulating the Secretion of Inflammatory Cytokines and Monocyte/Macrophage Subsets
por: Liu, Weiwei, et al.
Publicado: (2018)

Murine Placental Erythroid Cells Are Mainly Represented by CD45(+) Immunosuppressive Erythroid Cells and Secrete CXCL1, CCL2, CCL3 and CCL4 Chemokines
por: Nazarov, Kirill, et al.
Publicado: (2023)

Role of CC chemokine CCL6/C10 as a monocyte chemoattractant in a murine acute peritonitis.
por: LaFleur, Andrew M, et al.
Publicado: (2004)

CCL2 nitration is a negative regulator of chemokine-mediated inflammation
por: Barker, Catriona E., et al.
Publicado: (2017)

Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2
por: Yang, Liuliu, et al.
Publicado: (2021)

Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2
por: Yang, Liuliu, et al.
Publicado: (2021)

A Fluorescent Activatable AND‐Gate Chemokine CCL2 Enables In Vivo Detection of Metastasis‐Associated Macrophages
por: Fernandez, Antonio, et al.
Publicado: (2019)

Resident stroma-secreted chemokine CCL2 governs myeloid-derived suppressor cells in the tumor microenvironment
por: Oo, May Wathone, et al.
Publicado: (2022)

The Chemokine CCL3 Regulates Myeloid Differentiation and Hematopoietic Stem Cell Numbers
por: Staversky, Rhonda J., et al.
Publicado: (2018)

Human Macrophage–derived Chemokine (MDC), a Novel Chemoattractant for Monocytes, Monocyte-derived Dendritic Cells, and Natural Killer Cells
por: Godiska, Ronald, et al.
Publicado: (1997)

Chemokine Lkn-1/CCL15 enhances matrix metalloproteinase-9 release from human macrophages and macrophage-derived foam cells
por: Kwon, Sang-Hee, et al.
Publicado: (2008)

Neuronal CC chemokines: the distinct roles of CCL21 and CCL2 in neuropathic pain
por: Biber, Knut, et al.
Publicado: (2014)

CCL17 and CCL22 chemokines are upregulated in human obesity and play a role in vascular dysfunction
por: Hueso, Luisa, et al.
Publicado: (2023)

Immune response CC chemokines CCL2 and CCL5 are associated with pulmonary sarcoidosis
por: Palchevskiy, Vyacheslav, et al.
Publicado: (2011)

Differential Regulation of CD4+ T Cell Adhesion to Cerebral Microvascular Endothelium by the β-Chemokines CCL2 and CCL3
por: Liu, Kenneth KY, et al.
Publicado: (2012)

Up-regulation of the chemokine CCL21 in the skin of subjects exposed to irritants
por: Eberhard, Yanina, et al.
Publicado: (2004)

Expression of the inflammatory chemokines CCL5, CCL3 and CXCL10 in juvenile idiopathic arthritis, and demonstration of CCL5 production by an atypical subset of CD8+ T cells
por: Pharoah, Daniel S, et al.
Publicado: (2006)

Sarcoidosis exosomes stimulate monocytes to produce pro-inflammatory cytokines and CCL2
por: Wahlund, Casper J. E., et al.
Publicado: (2020)

CCL2-induced chemokine cascade promotes breast cancer metastasis by enhancing retention of metastasis-associated macrophages
por: Kitamura, Takanori, et al.
Publicado: (2015)

Chemokines are secreted by monocytes following OK-432 (lyophilized Streptococcus pyogenes) stimulation
por: Olsnes, Carla, et al.
Publicado: (2009)

Chemokines during anaphylaxis: the importance of CCL2 and CCL2-dependent chemotactic activity for basophils
por: Vantur, Romana, et al.
Publicado: (2020)

Mild COVID-19 imprints a long-term inflammatory eicosanoid- and chemokine memory in monocyte-derived macrophages
por: Bohnacker, Sina, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_nv836u49hip4t6phuja80v2djb