Enhancement of blood–brain barrier permeability is required for intravenously administered virus neutralizing antibodies to clear an established rabies virus infection from the brain and prevent the development of rabies in mice

Rabies virus (RABV) is a neurotropic virus that causes fatal disease in humans and animals. Currently there is no cure for rabies once clinical signs appear. It is believed that once RABV enters the central nervous system (CNS), virus neutralizing antibodies (VNAs) in the periphery cannot pass throu...

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Detalles Bibliográficos
Autores principales: Huang, Chien-Tsun, Li, Zhenguang, Huang, Ying, Zhang, Guoqing, Zhou, Ming, Chai, Qingqing, Wu, Hua, Fu, Zhen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171353/
https://www.ncbi.nlm.nih.gov/pubmed/25108172
http://dx.doi.org/10.1016/j.antiviral.2014.07.013

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